Endocrine Abstracts

Introduction: Papillary microcarcinomas tirodieos (MCT) are tumours less than or equal to centimeter size, mostly indectectables in the clinic and found incidentally after a thyroidectomy performed for another reason, management is under discussion and its prevalence is increased ~30%, it is believed that the increased use of thyroid ultrasound.Review: 16 patients with MCT in a province of southern Spain and evaluate the clinical and prognostic variables...

Introduction: Human recombinant growth hormone (hrGH) treatment in adult patients with GH deficiency (GHD) has an important interindividual variability and several factors can influence it. The aims of the study were: i)- to analyze the genotype of GHR regarding exon 3 deletion (d3-GHR) in a serie of adult patients with GHD; ii)- to assess the effect of d3-GHR on initial IGF1 levels; iii)- to evaluate if d3-GHR and/or initial IGF1 levels were associated with adverse effects an...

Introduction: Hypothyroidism is the most frequent thyroid disorder in patients with systemic lupus erythematosus (SLE) but the cause of this association is not well established. Moreover, no studies focused on the possible relationship between some specific immunologic patterns of SLE and the development of hypothyroidism have been reported.Methods: In our study, we determined the immunological features and the thyroid status of 103 consecutive patients ...

Background: Anaplastic carcinoma and primary lymphoma (TL) each constitute <2% of thyroid malignancies and are difficult to distinguish clinically. Both typically present with rapidly enlarging anterior neck masses in the elderly. Both may cause pressure symptoms (e.g. dysphagia, stridor and hoarseness). Differentiation is imperative as their treatment and prognoses differ.Case report: A 68-year-old man presented with a rapidly enlarging thyroid mass...

The pituitary is an anatomically well protected endocrine gland in permanent contact with the central nervous system. Although it was known that pituitary has plasticity in response to the physiological demands of the body, there were few clear data about the post-natal mechanisms in charge of this plasticity. The discovery of a group of cells expressing stem cell markers precisely organized in the outer zone of the adenopituitary open up new possibilities to explain the const...

Introduction: Childhood-onset hypopituitarism is an uncommon yet increasingly diagnosed disorder. As endocrinologists, we generally deal with the complexities of hormonal replacement and, when required, follow these patients to detect tumor recurrences. However, some causes of childhood- onset-hypopituitarism have comorbidities which can significantly increase morbi-mortality. We present the case of a 21-year-old girl who was diagnosed with ROHHAD syndrome.<p class="abstex...

Hypopituitarism is associated with increased morbidity and mortality compared to healthy population. However, the factors influencing prognosis are still not well known.Objectives: To determine the causes of mortality in adult patients with hypopituitarism and compare the mortality rate with general populationTo identify the factors associated with mortality and survival.Patients: Two hundred and nine adult p...

To evaluate the prevalence of comorbilities related to acromegaly and the grade of response to the different therapeutic alternatives.Material-methods: A retrospective study of 25 acromegalic patients diagnosed between 1990–2010 was made. It included a descriptive analysis on sex, age, hypertension, impaired glucose metabolism when diagnosed acromegaly, screening for dygestive and cardiac pathology, tumoral size, and percentage of disease control an...

Bilateral cervical exploration has been the gold standard in parathyroid surgery. Nowadays, the preoperative localization procedures have facilitated the minimally invasive surgery. This study aims to analyze the influence of thyroid disease in Tc99m-sestamibi scintigraphy (MIBI) results.A series of 154 patients with PHP who underwent parathyroidectomy was reviewed. Patients were divided into two groups: group 1 (G1, 58 patients) with thyroid diseases, a...

Objective: To determine the prevalence of polycystic ovary syndrome (PCOS) and hyperandrogenism and their relationships with metabolic syndrome (MS) parameters in female-to-male transsexuals (FMT).Design and methods: Seventy-seven FMT were assessed clinically and biochemically to hyperandrogenism, before the beginning of the treatment with testosterone. We also assessed cardiovascular risk factors and other parameters of MS.Results...